BDBM50461890 CHEMBL4228971

SMILES Cc1ccc(c(n1)Cl)c2ccc(cc2)c3c(c(c4cc(ccc4n3)F)C(=O)O)C

InChI Key InChIKey=NPMKPVGSRBWMIO-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50461890   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50461890(CHEMBL4228971)
Affinity DataIC50: 26nMAssay Description:Inhibition of DHODH (unknown origin) expressed in Escherichia coli Rosetta2(DE3) assessed as reduction of DCIP using dihydroorotate as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)