BDBM50461878 CHEMBL4228712

SMILES Cc1c(nc2ccc(F)cc2c1C(O)=O)-c1ccc(cc1)-c1cccnc1Cl

InChI Key InChIKey=YORBMWZTUVVMNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50461878   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50461878(CHEMBL4228712)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of DHODH (unknown origin) expressed in Escherichia coli Rosetta2(DE3) assessed as reduction of DCIP using dihydroorotate as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed