BDBM50461870 CHEMBL4227002

SMILES OC(=O)c1cc(nc2ccccc12)-c1ccc(cc1)-c1cccnc1C(F)(F)F

InChI Key InChIKey=FYXZUHQGTBSSGB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50461870   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50461870(CHEMBL4227002)
Affinity DataIC50: 148nMAssay Description:Inhibition of DHODH (unknown origin) expressed in Escherichia coli Rosetta2(DE3) assessed as reduction of DCIP using dihydroorotate as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed