BDBM50461735 CHEMBL4228488

SMILES CCCCn1c(Sc2cccc(OC)c2)c(C)c2c(N)nc(N)nc12

InChI Key InChIKey=HDNKCXNGZLCJHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50461735   

TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50461735(CHEMBL4228488)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human recombinant DHFR expressed in Escherichia coli Rosetta Gami B (DE3) competent cells using DHFA as substrate and NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50461735(CHEMBL4228488)
Affinity DataIC50: 73nMAssay Description:Inhibition of Pneumocystis jirovecii recombinant DHFR expressed in Escherichia coli Rosetta Gami B (DE3) competent cells using DHFA as substrate and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed