BDBM50461649 CHEMBL4225519

SMILES COc1cc(cnc1OC)C(=O)N1CC[C@H](NC(=O)c2ccccc2OC(F)(F)F)c2c1cnn2C(C)C

InChI Key InChIKey=MOKGQUKWOUYHHS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50461649   

TargetSerine palmitoyltransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50461649(CHEMBL4225519)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of human SPT2 transfected in Freestyle293 cells using L-serine and palmitoyl-CoA as substrate preincubated for 60 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine palmitoyltransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50461649(CHEMBL4225519)
Affinity DataIC50: 0.760nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine palmitoyltransferase 3(Homo sapiens)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50461649(CHEMBL4225519)
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed