BDBM50461633 CHEMBL4227896

SMILES C=CC(=O)NCCCC[C@H](NC(=O)Cc1ccccc1)C(=O)N1CCN(CC1)c1cccnc1

InChI Key InChIKey=XKRSVEVWHGGAPK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50461633   

TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Helmholtz-Zentrum Dresden-Rossendorf

Curated by ChEMBL
LigandPNGBDBM50461633(CHEMBL4227896)
Affinity DataKi:  2.60E+3nMAssay Description:Irreversible inhibition of human TGase 2 using Z-Glu(HMC)-Gly-OH as substrate measured at 20 secs interval over 900 secs by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Helmholtz-Zentrum Dresden-Rossendorf

Curated by ChEMBL
LigandPNGBDBM50461633(CHEMBL4227896)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of TG2 (unknown origin) using Cbz-Glu(gamma-p-nitrophenyl ester)Gly (AL5) as substrate and measured by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed