BDBM50461498 CHEMBL4227101

SMILES COc1ccccc1OC(=O)N1CCC(CC1)C(=O)N[C@@H](CC(O)=O)C(=O)COc1c(F)c(F)cc(F)c1F

InChI Key InChIKey=ONTVHQCNANDOIU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50461498   

TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461498(CHEMBL4227101)
Affinity DataIC50: 20nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed