BDBM50461429 CHEMBL4227326

SMILES [H][C@]12[C@@H](CC[C@]1(CNCCc1ccccn1)CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)CC=C(c4ccc(cc4)C(O)=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(C)=C

InChI Key InChIKey=IPORZYJGANVTDB-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50461429   

TargetGag-Pol polyprotein(HIV-1)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461429(CHEMBL4227326)
Affinity DataEC50:  16nMAssay Description:Binding affinity to CA-SP1 P373S mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461429(CHEMBL4227326)
Affinity DataEC50:  8nMAssay Description:Binding affinity to CA-SP1 P373S mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50461429(CHEMBL4227326)
Affinity DataIC50: 19nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed