BDBM50461308 CHEMBL4228117

SMILES CC1=C(C(NC(=O)N1)c1ccc(F)c(CCC(=O)NCC2(C)CCCCC2)c1)C(=O)Nc1ccc2[nH]ncc2c1

InChI Key InChIKey=XCHIXWGYCFFINH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50461308   

TargetG protein-coupled receptor kinase 5(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50461308(CHEMBL4228117)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GRK5 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50461308(CHEMBL4228117)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRhodopsin kinase GRK1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50461308(CHEMBL4228117)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GRK1 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed