BDBM50461257 CHEMBL4228343

SMILES COc1ccc(CC(NC(=O)c2ccc(cc2)-c2ccccc2)C(=O)NC2(CC2)C#N)cn1

InChI Key InChIKey=XCDSVESMDJKIDL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50461257   

TargetCathepsin K(Human)
Irbm Science Park

Curated by ChEMBL
LigandPNGBDBM50461257(CHEMBL4228343)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
Irbm Science Park

Curated by ChEMBL
LigandPNGBDBM50461257(CHEMBL4228343)
Affinity DataIC50: 178nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin S(Human)
Irbm Science Park

Curated by ChEMBL
LigandPNGBDBM50461257(CHEMBL4228343)
Affinity DataIC50: 195nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
Irbm Science Park

Curated by ChEMBL
LigandPNGBDBM50461257(CHEMBL4228343)
Affinity DataIC50: 4.08E+3nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Irbm Science Park

Curated by ChEMBL
LigandPNGBDBM50461257(CHEMBL4228343)
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed