BDBM50461070 CHEMBL4227173::US10457637, Compound 2

SMILES CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(OCC2CCOCC2)c(c1)S(C)(=O)=NC

InChI Key InChIKey=HOSGNAGMZQGRJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50461070   

TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461070(CHEMBL4227173 | US10457637, Compound 2)
Affinity DataIC50: 290nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461070(CHEMBL4227173 | US10457637, Compound 2)
Affinity DataIC50: 550nMAssay Description:The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
Go to US Patent