BDBM50460921 CHEMBL4225563

SMILES C(CN1CCCCC1)NCc1cc(CNCCN2CCCCC2)cc(Nc2ccccc2CN2CCOCC2)c1

InChI Key InChIKey=PAFMRDKEWWXTBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50460921   

TargetAmyloid-beta precursor protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50460921(CHEMBL4225563)
Affinity DataIC50: 6.60E+3nMAssay Description:Modulation of human wild-type APP695 expressed in SH-SY5Y cells assessed as inhibition of amyloid beta (1 to 40 residues) production measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50460921(CHEMBL4225563)
Affinity DataIC50: 7.90E+3nMAssay Description:Modulation of human wild-type APP695 expressed in SH-SY5Y cells assessed as inhibition of amyloid beta (1 to 42 residues) production measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed