BDBM50460863 CHEMBL4227228

SMILES C[C@@H](NC(=O)c1cc(cc(c1)-c1ccc(C)cn1)C1=NO[C@@H](C1)c1ccccn1)c1ccc(F)cn1

InChI Key InChIKey=SUXRXYKUAHNUAX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50460863   

TargetUDP-glucuronosyltransferase 1A1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50460863(CHEMBL4227228)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human UGT1A1 expressed in baculovirus infected insect cells using bilirubin as substrate measured after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50460863(CHEMBL4227228)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Flp-In-293 cells assessed as inhibition of CTP-induced chloride current response ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50460863(CHEMBL4227228)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed