BDBM50460549 CHEMBL4228379

SMILES Cn1cncc1-c1ncc(-c2ncc(-c3ncc(-c4ccccc4)n3C)n2C)n1C

InChI Key InChIKey=JYKZQFAVSJPBQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50460549   

TargetProprotein convertase subtilisin/kexin type 9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50460549(CHEMBL4228379)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of binding of full-length recombinant human PCSK9 (M1 to Q692 residues) expressed in HEK293 cells to full-length LDLR (A1 to A699 residues...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed