BDBM50460548 CHEMBL4227596

SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(O)=O

InChI Key InChIKey=TXBZYZFAEKWONN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50460548   

TargetProprotein convertase subtilisin/kexin type 9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50460548(CHEMBL4227596)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PCSK9 binding to LDLR in human HuH7 cells after 5 hrs by On-cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed