BDBM50460483 CHEMBL4228186

SMILES Oc1c(cc([N+]([O-])=O)c2cccnc12)C(=O)N(CC#N)Cc1ccccc1

InChI Key InChIKey=WQIVRKSDUXZLRE-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50460483   

TargetCathepsin B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50460483(CHEMBL4228186)
Affinity DataKi:  3.20E+4nMAssay Description:Mixed inhibition of recombinant human cathepsin B exopeptidase activity assessed as inhibitory constant for enzyme-substrate-inhibitor complex using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50460483(CHEMBL4228186)
Affinity DataKi:  6.40E+4nMAssay Description:Mixed inhibition of recombinant human cathepsin B endopeptidase activity assessed as inhibitory constant for enzyme-substrate-inhibitor complex using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50460483(CHEMBL4228186)
Affinity DataKi:  1.32E+5nMAssay Description:Competitive inhibition of recombinant human cathepsin B endopeptidase activity assessed as inhibitory constant for enzyme-inhibitor complex using Z-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50460483(CHEMBL4228186)
Affinity DataKi:  1.82E+5nMAssay Description:Mixed inhibition of recombinant human cathepsin B endopeptidase activity assessed as inhibitory constant for enzyme-inhibitor complex using Z-Arg-Arg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50460483(CHEMBL4228186)
Affinity DataKi:  1.85E+5nMAssay Description:Mixed inhibition of recombinant human cathepsin B exopeptidase activity assessed as inhibitory constant for enzyme-inhibitor complex using Abz-Gly-Il...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed