BDBM50460468 CHEMBL4226631

SMILES COC(=O)Nc1ccc(cc1)-c1cc(nnc1C)[C@H](Cc1ccccc1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1

InChI Key InChIKey=ARGAWPOUZMCKAP-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50460468   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50460468(CHEMBL4226631)
Affinity DataKi:  10nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate measured after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50460468(CHEMBL4226631)
Affinity DataKi:  1.37E+3nMAssay Description:Inhibition of human plasma kallikreinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50460468(CHEMBL4226631)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTrypsin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50460468(CHEMBL4226631)
Affinity DataKi: >6.22E+3nMAssay Description:Inhibition of human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50460468(CHEMBL4226631)
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50460468(CHEMBL4226631)
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of human factor 7aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50460468(CHEMBL4226631)
Affinity DataKi: >1.47E+4nMAssay Description:Inhibition of human TPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50460468(CHEMBL4226631)
Affinity DataKi: >2.97E+4nMAssay Description:Inhibition of human urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50460468(CHEMBL4226631)
Affinity DataKi:  3.93E+4nMAssay Description:Inhibition of human factor 9aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPlasminogen(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50460468(CHEMBL4226631)
Affinity DataKi: >5.34E+4nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50460468(CHEMBL4226631)
Affinity DataKi: >6.44E+4nMAssay Description:Inhibition of human activated protein CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed