BDBM50460373 CHEMBL4226396

SMILES CN1CC2CCC1(CC2)[C@H](NC(=O)c1ccnc(c1F)C(F)(F)F)c1ccccc1

InChI Key InChIKey=FRSDNHPZGYIHJH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50460373   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50460373(CHEMBL4226396)Copy SMILESCopy InChI

Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant human GlyT1 expressed in CHO cells assessed as reduction in [3H]glycine uptake pretreated for 15 mins followed by [3H]glyci...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL