BDBM50460238 CHEMBL4227563

SMILES Cc1ccc(cc1Br)-c1nc(O)c(O)c(n1)C(O)=O

InChI Key InChIKey=WHVBNKJFDMLSTR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50460238   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50460238(CHEMBL4227563)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 polymerase M184V mutant using PPT57 DNA/Cy5-labeled PPT24 as template/primer preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50460238(CHEMBL4227563)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 polymerase K65R mutant using PPT57 DNA/Cy5-labeled PPT24 as template/primer preincubated for 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50460238(CHEMBL4227563)
Affinity DataIC50: 4.63E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 polymerase E89K mutant using PPT57 DNA/Cy5-labeled PPT24 as template/primer preincubated for 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50460238(CHEMBL4227563)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 polymerase using PPT57 DNA/Cy5-labeled PPT24 as template/primer preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50460238(CHEMBL4227563)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 RNase H preincubated for 10 mins followed by PBS-22dpol/radiolabeled PBS-14r8d addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed