BDBM50460163 CHEMBL4228601

SMILES CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(cc3)C3=Nc4cscc4NC(=O)C3)cc2C(F)(F)F)CC1

InChI Key InChIKey=OKHZIVXQKINVAO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50460163   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50460163(CHEMBL4228601)
Affinity DataIC50: 72nMAssay Description:Inhibition of RET (unknown origin) after 40 mins in presence of [gamma-33P]-ATP by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50460163(CHEMBL4228601)
Affinity DataIC50: 28nMAssay Description:Inhibition of FLT3 (unknown origin) after 40 mins in presence of [gamma-33P]-ATP by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50460163(CHEMBL4228601)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human FMS using myelin basic protein as substrate after 40 mins in presence of [gamma-33P]-ATP by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50460163(CHEMBL4228601)
Affinity DataIC50: 63nMAssay Description:Inhibition of PDGFRb (unknown origin) after 40 mins in presence of [gamma-33P]-ATP by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed