BDBM50460059 CHEMBL4226300

SMILES OC[C@H](O)CONC(=O)c1cc2CCOc2c(F)c1Nc1ccc(I)cc1F

InChI Key InChIKey=RKPWJQOZGFKGHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50460059   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50460059(CHEMBL4226300)
Affinity DataIC50: 6nMAssay Description:Inhibition of MEK1 (unknown origin) using Ser/Thr 03 peptide substrate after 4 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed