BDBM50459529 CHEMBL4208878

SMILES NCc1ccc(NC(=O)c2c([O-])ccc[n+]2Cc2nccn2Cc2ccccc2)cc1

InChI Key InChIKey=DMRCMJXUFJLJKH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50459529   

TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50459529(CHEMBL4208878)
Affinity DataIC50: 180nMAssay Description:Inhibition of trypsin (unknown origin) pre-incubated for 30 mins before N-Boc-FSR-AMC substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50459529(CHEMBL4208878)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of thrombin (unknown origin) pre-incubated for 30 mins before N-Boc-FSR-AMC substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50459529(CHEMBL4208878)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of factor 10a (unknown origin) pre-incubated for 30 mins before N-Boc-FSR-AMC substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetKallikrein-6(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50459529(CHEMBL4208878)
Affinity DataIC50: 890nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed