BDBM50459364 CHEMBL4210060::US10751335, Example 1
SMILES Fc1cc(Br)ccc1CN1CCC(CC1)n1c2cc(Cl)c(Cl)cc2[nH]c1=O
InChI Key InChIKey=FOIPWNCFVUKDPZ-UHFFFAOYSA-N
Data 6 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50459364
Affinity DataEC50: 91nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed in human USOS-beta-arrestin-hMOR-PathHunter cells incubated for 90 mins by beta-arrestin-2 enz...More data for this Ligand-Target Pair
Affinity DataEC50: 67nMAssay Description:A standard [35S]GTPγS binding assay in membranes prepared from CHO cells expressing the human MOR was performed in a concentration response mann...More data for this Ligand-Target Pair
Affinity DataEC50: 89nMAssay Description:he CisBio cAMP cell based assay kit that uses HTRF technology was utilized to assess MOR-mediated inhibition of cAMP. Assays were performed according...More data for this Ligand-Target Pair
Affinity DataEC50: 91nMAssay Description:Inhibition of mu-opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of mu-opioid receptor (unknown origin) assessed as increase in beta-arrestin-2 recruitment by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair