BDBM50459363 CHEMBL4202958::US10751335, Example 4
SMILES Fc1cc(Br)ccc1CN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
InChI Key InChIKey=WBECKUWCFNXRGX-UHFFFAOYSA-N
Data 8 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50459363
Affinity DataEC50: 355nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed in human USOS-beta-arrestin-hMOR-PathHunter cells incubated for 90 mins by beta-arrestin-2 enz...More data for this Ligand-Target Pair
Affinity DataEC50: 223nMAssay Description:A standard [35S]GTPγS binding assay in membranes prepared from CHO cells expressing the human MOR was performed in a concentration response mann...More data for this Ligand-Target Pair
Affinity DataEC50: 319nMAssay Description:he CisBio cAMP cell based assay kit that uses HTRF technology was utilized to assess MOR-mediated inhibition of cAMP. Assays were performed according...More data for this Ligand-Target Pair
Affinity DataEC50: 220nMAssay Description:A standard [35S]GTPγS binding assay in membranes prepared from CHO cells expressing the human MOR was performed in a concentration response mann...More data for this Ligand-Target Pair
Affinity DataEC50: 950nMAssay Description:A standard [35S]GTPγS binding assay in membranes prepared from CHO cells expressing the human MOR was performed in a concentration response mann...More data for this Ligand-Target Pair
Affinity DataEC50: 355nMAssay Description:Inhibition of mu-opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of mu-opioid receptor (unknown origin) assessed as increase in beta-arrestin-2 recruitment by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair