BDBM50458769 CHEMBL4218229

SMILES COc1cccc2cc(oc12)C(=O)NCNC(=O)[C@@H](CN(O)C=O)Cc1ccccc1

InChI Key InChIKey=SEQGTCONQYABAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50458769   

TargetMacrophage metalloelastase(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458769(CHEMBL4218229)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458769(CHEMBL4218229)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed