BDBM50458762 CHEMBL4207308

SMILES CCCCC[C@H]([C@@H](CC)N(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1ccccc1

InChI Key InChIKey=PEIHYHWPPPLALT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50458762   

TargetMacrophage metalloelastase(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458762(CHEMBL4207308)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTolloid-like protein 2(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458762(CHEMBL4207308)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human N-terminal 6His-tagged TLL2 (26 to 1015 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTolloid-like protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458762(CHEMBL4207308)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full length TLL1 using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2) as substrate preincubated for 10 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458762(CHEMBL4207308)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed