BDBM50458750 CHEMBL4210320

SMILES CS(=O)(=O)Cc1cc(nc(n1)N1CCOCC1)-c1cnc(N)cc1C(F)(F)F

InChI Key InChIKey=IPAWIEAHHPWPAU-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50458750   

TargetSerine/threonine-protein kinase mTOR(Human)
Shanghai Haiyan Pharmaceutical Technology

Curated by ChEMBL

LigandBDBM50458750(CHEMBL4210320)Copy SMILESCopy InChI

Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4EBP1 a...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
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TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Shanghai Haiyan Pharmaceutical Technology

Curated by ChEMBL

LigandBDBM50458750(CHEMBL4210320)Copy SMILESCopy InChI

Affinity DataIC50: 189nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL