BDBM50458636 CHEMBL4206624

SMILES CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(NCCCN2CCCCC2)C1=O

InChI Key InChIKey=APIABORIIIFDEJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50458636   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50458636(CHEMBL4206624)
Affinity DataIC50: 4.21E+3nMAssay Description:Inhibition of endothelial lipase in human HT1080 cells using HDL as substrate pretreated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEndothelial lipase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50458636(CHEMBL4206624)
Affinity DataIC50: 25nMAssay Description:Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed