BDBM50458629 CHEMBL4210670

SMILES CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(cc3)-c3ccc(=O)[nH]c3)cc2C(F)(F)F)CC1

InChI Key InChIKey=LBELDIIRDVZLHQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50458629   

TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50458629(CHEMBL4210670)
Affinity DataIC50: 95nMAssay Description:Inhibition of human KDR using cisbio TK biotin-peptide as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50458629(CHEMBL4210670)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human RET using cisbio TK biotin-peptide as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr by HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed