BDBM50458468 CHEMBL4216101

SMILES CCC1(CCN(CC1)C(=O)OC(C)(C)C)OC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)S([O-])(=O)=O

InChI Key InChIKey=XQPCHNVZRFSEQT-UHFFFAOYSA-M

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50458468   

TargetReplicase polyprotein 1ab(MERS-CoV)
Wichita State University

Curated by ChEMBL
LigandPNGBDBM50458468(CHEMBL4216101)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of Middle East respiratory syndrome-related coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
Wichita State University

Curated by ChEMBL
LigandPNGBDBM50458468(CHEMBL4216101)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of SARS coronavirus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(FCoV)
Wichita State University

Curated by ChEMBL
LigandPNGBDBM50458468(CHEMBL4216101)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of Feline infectious peritonitis virus 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate incubated for 30 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed