BDBM50457950 CHEMBL4217007

SMILES COc1ccc(\C=N\NC(=O)CCCn2c(NCc3ccccc3)nc3n(C)c(=O)n(C)c(=O)c23)c(O)c1

InChI Key InChIKey=VIWWFFQWMHWPCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457950   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50457950(CHEMBL4217007)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human GST-tagged PDE4B expressed in baculovirus infected Sf9 insect cells using cAMP as substrate after 10 mins by PDE-Glo Phosphodiest...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50457950(CHEMBL4217007)
Affinity DataIC50: 5.28E+4nMAssay Description:Inhibition of human GST-tagged PDE7A expressed in baculovirus infected Sf9 insect cells using cAMP as substrate after 10 mins by PDE-Glo Phosphodiest...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed