BDBM50457925 CHEMBL4207316

SMILES CCc1c([nH]c2ccc(cc12)C(F)(F)F)C(=O)NC(CO)Cc1ccccc1

InChI Key InChIKey=QNHQLBLUWHLFSC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457925   

TargetSerine/threonine-protein kinase B-raf(Mouse)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457925(CHEMBL4207316)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457925(CHEMBL4207316)
Affinity DataIC50: 900nMAssay Description:Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed