BDBM50457923 CHEMBL4209588

SMILES Cc1c([nH]c2ccc(Cl)cc12)C(=O)NC(CO)Cc1ccccc1

InChI Key InChIKey=MJOHDUGXCLBUJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457923   

TargetEpidermal growth factor receptor(Human)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457923(CHEMBL4209588)
Affinity DataIC50: 500nMAssay Description:Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457923(CHEMBL4209588)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed