BDBM50457878 CHEMBL4209824

SMILES Cc1ccccc1NC(=O)N1CCN(CC1)c1nc(N)nc2scnc12

InChI Key InChIKey=NLTFWQLJQFCXHT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457878   

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457878(CHEMBL4209824)
Affinity DataIC50: 150nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457878(CHEMBL4209824)
Affinity DataIC50: 114nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed