BDBM50457772 CHEMBL4211480

SMILES Oc1ccc(cc1)C(=O)c1c2C(=O)OCc2ccc1-c1ccc(O)cc1

InChI Key InChIKey=PXBJKBXSEIJNMT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50457772   

Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457772(CHEMBL4211480)
Affinity DataIC50: 8.12E+4nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457772(CHEMBL4211480)
Affinity DataIC50: 4.09E+4nMAssay Description:Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457772(CHEMBL4211480)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed