BDBM50457619 CHEMBL2441066

SMILES O=S1(=O)NCN(C2CC2)c2ccccc12

InChI Key InChIKey=RNCMFTYXIWRXJD-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50457619   

TargetGlutamate receptor 2(Human)
University of Liege

Curated by ChEMBL
LigandPNGBDBM50457619(CHEMBL2441066)
Affinity DataEC50:  9.06E+3nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
University of Liege

Curated by ChEMBL
LigandPNGBDBM50457619(CHEMBL2441066)
Affinity DataEC50:  9.12E+3nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutamate receptor 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50457619(CHEMBL2441066)
Affinity DataEC50:  4.17E+3nMAssay Description:Positive allosteric modulation of GluA2 receptor in rat embryonic cortex neuron assessed as increase of AMPA-induced membrane depolarization by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed