BDBM50457524 CHEMBL4218025

SMILES CCc1cccc(NC(=O)c2cc(cc3cccnc23)C(F)(F)c2cncnc2)n1

InChI Key InChIKey=HEUCNNISZPLMTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457524   

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50457524(CHEMBL4218025)
Affinity DataIC50: 3.63E+3nMAssay Description:Negative allosteric modulator activity at rat mGlu5 receptor expressed in HEK293A cells assessed as inhibition of EC80 glutamate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50457524(CHEMBL4218025)
Affinity DataIC50: 3.60E+3nMAssay Description:Negative allosteric modulator activity at rat mGlu5 receptor expressed in HEK293A cells assessed as inhibition of EC80 glutamate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed