BDBM50457439 CHEMBL4213357

SMILES Clc1ccc(cc1)C(=O)Nc1c(nc2c(Br)cc(Br)cn12)-c1cccs1

InChI Key InChIKey=MEWSBNIVOLYKGU-UHFFFAOYSA-N

Data  12 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50457439   

TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 370nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3delta expressed in HEK293 cell membranes after 90 mins in presence of GABA by liquid sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  870nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3gamma2 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  150nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha4beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  100nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha1beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  100nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha1beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 630nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta2 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 510nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha4beta3delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 1.86E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha4beta3 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  170nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 790nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 960nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes after 90 mins in presence of GABA by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  130nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  60nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha4beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  2.01E+3nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha1beta3gamma2 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta2delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 1.13E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta2gamma2 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 930nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3gamma2 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 3.29E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha4beta3gamma2 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataIC50: 1.09E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3gamma2 expressed in HEK293 cell membranes after 90 mins in presence of GABA by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed