BDBM50457207 CHEMBL4215216

SMILES COc1cccc(\C=C(/C#N)c2nc3ccccc3[nH]2)c1

InChI Key InChIKey=RDSCFLMCSMCAAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457207   

TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457207(CHEMBL4215216)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50457207(CHEMBL4215216)
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of Plasmodium falciparum FP-2 using Z-Phe-Arg-AMC as substrate pretreated with enzyme for 10 mins followed by susbtrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed