BDBM50457151 CHEMBL4208328

SMILES CC(C)Cc1ccc(cc1)C(C)C1(O)CSC1

InChI Key InChIKey=FCRGVNBFEMCRGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457151   

TargetProstaglandin G/H synthase 1/2(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50457151(CHEMBL4208328)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX in RBL1 cells assessed as reduction in PGE2/D2 production using A23187-induced arachidonic acid as substrate preincubated for 2 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50457151(CHEMBL4208328)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of 5-LOX in RBL1 cells assessed as reduction in LTB4 production using A23187-induced arachidonic acid as substrate preincubated for 2 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed