BDBM50456585 CHEMBL4218664

SMILES COc1ccc(cc1)-c1cn(C[C@H]2NC[C@@H](O)[C@H]2O)nn1

InChI Key InChIKey=ULCQBQQZAQOXJM-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50456585   

TargetAlpha-galactosidase(Arabian coffee)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50456585(CHEMBL4218664)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of coffee beans alpha-galactosidase using p-nitrophenyl glycopyranoside preincubated for 5 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50456585(CHEMBL4218664)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-galactosidase(Bovine)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50456585(CHEMBL4218664)
Affinity DataIC50: 3.38E+5nMAssay Description:Inhibition of bovine liver beta-galactosidase using p-nitrophenyl glycopyranoside preincubated for 5 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50456585(CHEMBL4218664)
Affinity DataIC50: 1.85E+5nMAssay Description:Inhibition of human lysosomal alpha-galactosidase A using 4-methylumbelliferyl-alpha-D-galactopyranoside as substrate preincubated for 45 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50456585(CHEMBL4218664)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50456585(CHEMBL4218664)
Affinity DataIC50: 1.85E+5nMAssay Description:Inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50456585(CHEMBL4218664)
Affinity DataKi:  1.90E+4nMAssay Description:Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
University of Seville

Curated by ChEMBL
LigandPNGBDBM50456585(CHEMBL4218664)
Affinity DataKi:  7.50E+4nMAssay Description:Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed