BDBM50456370 CHEMBL4211185

SMILES Nc1ncnc2n(nc(-c3ccc(Br)c(O)c3)c12)C1CCc2ccccc12

InChI Key InChIKey=ARUHNGYBTHMQAU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50456370   

LigandPNGBDBM50456370(CHEMBL4211185)
Affinity DataIC50: 155nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50456370(CHEMBL4211185)
Affinity DataIC50: 123nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50456370(CHEMBL4211185)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of human recombinant FLAG-tagged full length ATR expressed in mammalian cell line co-expressing human recombinant cMyc-tagged full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed