BDBM50456345 CHEMBL4210146

SMILES Cc1cnc(nc1)Nc2cnn(c2C)C

InChI Key InChIKey=XMVHLWOPQDOPRZ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50456345   

TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50456345(CHEMBL4210146)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of full length human N-terminal MAHHHHHH-tagged ERK2 expressed in Escherichia coli BL21 (DE3) using ATF2-GFP as substrate after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)