BDBM50456057 CHEMBL4218254

SMILES COc1ccc2cc(ccc2c1)C(C)C(=O)NCCOc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=PXTIXWMAPRZGGO-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50456057   

TargetCarbonic anhydrase 12(Human)
Ege University Bornova

Curated by ChEMBL
LigandPNGBDBM50456057(CHEMBL4218254)
Affinity DataKi:  7.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University Bornova

Curated by ChEMBL
LigandPNGBDBM50456057(CHEMBL4218254)
Affinity DataKi:  7.80nMAssay Description:Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Ege University Bornova

Curated by ChEMBL
LigandPNGBDBM50456057(CHEMBL4218254)
Affinity DataKi:  21nMAssay Description:Inhibition of recombinant human carbonic anhydrase-9 catalytic domain incubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Ege University Bornova

Curated by ChEMBL
LigandPNGBDBM50456057(CHEMBL4218254)
Affinity DataKi:  73nMAssay Description:Inhibition of recombinant human carbonic anhydrase-4 incubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ege University Bornova

Curated by ChEMBL
LigandPNGBDBM50456057(CHEMBL4218254)
Affinity DataKi:  74nMAssay Description:Inhibition of recombinant human carbonic anhydrase-1 incubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed