BDBM50456051 CHEMBL4214565

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NCCCCOc3ccc(cc3)S(N)(=O)=O)c2c1

InChI Key InChIKey=OWXCNNFFXOOPBZ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50456051   

TargetCarbonic anhydrase 9(Human)
Ege University Bornova

Curated by ChEMBL
LigandPNGBDBM50456051(CHEMBL4214565)
Affinity DataKi:  7.70nMAssay Description:Inhibition of recombinant human carbonic anhydrase-9 catalytic domain incubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University Bornova

Curated by ChEMBL
LigandPNGBDBM50456051(CHEMBL4214565)
Affinity DataKi:  8.10nMAssay Description:Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Ege University Bornova

Curated by ChEMBL
LigandPNGBDBM50456051(CHEMBL4214565)
Affinity DataKi:  64nMAssay Description:Inhibition of recombinant human carbonic anhydrase-12 incubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ege University Bornova

Curated by ChEMBL
LigandPNGBDBM50456051(CHEMBL4214565)
Affinity DataKi:  87nMAssay Description:Inhibition of recombinant human carbonic anhydrase-1 incubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Ege University Bornova

Curated by ChEMBL
LigandPNGBDBM50456051(CHEMBL4214565)
Affinity DataKi:  8.14E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase-4 incubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed