BDBM50455630 CHEMBL4216648

SMILES COC(=O)N[C@H](C(=O)NN(C[C@H](OC(=O)[C@@H](NC(=O)OC)C(C)(C)C)[C@H](Cc1ccccc1)NC(=O)OC(OC(=O)[C@@H](N)C(C)C)C(C)C)Cc1ccc(cc1)-c1ccccn1)C(C)(C)C

InChI Key InChIKey=YOHNRXJNQMSDBT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50455630   

TargetProtease(Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50455630(CHEMBL4216648)
Affinity DataEC50:  5.30nMAssay Description:Inhibition of HIV1 NL4-3 protease assessed as decrease in viral replication in human MT2 cells after 4 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed