BDBM50455589 CHEMBL4213984

SMILES COc1cc2CNCc2cc1-n1cnc2ccc(cc12)-c1ccnc2[nH]ccc12

InChI Key InChIKey=RFUHKEPWGZUNBG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50455589   

TargetProtein kinase C iota type(Human)
Agency For Science, Technology and Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM50455589(CHEMBL4213984)
Affinity DataIC50: 48nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Agency For Science, Technology and Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM50455589(CHEMBL4213984)
Affinity DataIC50: 560nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-epsilon expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Agency For Science, Technology and Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM50455589(CHEMBL4213984)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Agency For Science, Technology and Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM50455589(CHEMBL4213984)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Agency For Science, Technology and Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM50455589(CHEMBL4213984)
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-zeta expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Agency For Science, Technology and Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM50455589(CHEMBL4213984)
Affinity DataIC50: 280nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed