BDBM50455475 CHEMBL1085588

SMILES C[S+]([O-])c1cc2n(C)c3c(cnn(Cc4cccc(N)c4)c3=O)c2s1

InChI Key InChIKey=ZWKJWVSEDISQIS-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50455475   

TargetPyruvate kinase PKM(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50455475(CHEMBL1085588)
Affinity DataEC50:  92nMAssay Description:Activation of recombinant human PKM2 expressed in Escherichia coli BL21 at 4 uM incubated for 50 mins measured over 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50455475(CHEMBL1085588)
Affinity DataEC50:  92nMAssay Description:Activation of human recombinant full length His-tagged PKM2 (Asp354, Lys311, Glu397, Gly315 residues)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed