BDBM50455184 CHEMBL4214945

SMILES COc1ccc(Br)cc1\C=C\c1nnc(o1)-c1cccc2c1[nH]c(=O)c1ccccc1c2=O

InChI Key InChIKey=MXPOAMZRHGVYIO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50455184   

TargetPoly [ADP-ribose] polymerase 1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50455184(CHEMBL4214945)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human GST-tagged PARP1 expressed in Escherichia coli using damaged DNA as substrate after 30 mins in presence of NAD+ by re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed