BDBM50454992 CHEMBL4214099

SMILES [H][C@]12C[C@@]1([H])c1cc3c(C(=O)NC)c(oc3cc1N(CC2)S(C)(=O)=O)-c1ccc(F)cc1

InChI Key InChIKey=HQHFICNBZSKHED-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50454992   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Presidio Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50454992(CHEMBL4214099)
Affinity DataEC50:  7nMAssay Description:Inhibition of HCV genotype 1b NS5B polymerase infected in human HuH7 replicon cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Presidio Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50454992(CHEMBL4214099)
Affinity DataEC50:  25nMAssay Description:Inhibition of HCV genotype 1a NS5A polymerase L31V/Y93H double mutant infected in human HuH7 replicon cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed